Diseases such as measles and the influenza were easily transmitted and caused the death of many Aborigines, who had no resistance like Europeans.

It was found that a genetic disorder, Porphyria Variegata, may have been carried by one of the crew.  This PV gene was prevalent in The Netherlands in the 17th century and carried by a young bride to to South Africa in 1688.  The disease was noticed in the area where Zuytdorp came to grief.

Similarly with the six fingers and six toes.  Again a genetic defect called "Ellis-van Creveld",named after two doctors, Ellis-van Creveld.  The jury is still out on the number of incidents.

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